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Product Overview
Coenzyme Q10 is a yellow to orange crystalline powder, odorless and tasteless, and is prone to decomposition when exposed to light. It is widely found in cell membranes, particularly in mitochondria, and is mainly distributed in the heart, lungs, liver, kidneys, spleen, pancreas, and adrenal glands. Although the total body content of Coenzyme Q10 is only 500-1500 mg, it plays a crucial role. It is a vital mediator in the mitochondrial electron transport chain, involved in ATP synthesis, which provides energy for muscle contraction and other essential cellular functions, impacting all cells, especially those with high energy demands such as the heart, lungs, liver, kidneys, spleen, pancreas, and adrenal glands. With aging, Coenzyme Q10 levels decrease, making it essential for heart health and potentially alleviating many age-related heart conditions.
Coenzyme Q10 Production Process
- Coenzyme Q10 Production from Pig Heart Residue
- (1) Saponification
- Ingredients Ratio: Pig heart residue: 95% ethanol: Sodium hydroxide: Pyrogallol = 1:1.3:0.13:0.12
- In a reaction vessel, mix ethanol, sodium hydroxide, and pyrogallol, then add pig heart residue after extraction of cytochrome C. Reflux at 78-90°C for 30 minutes, cool to 35°C to obtain saponified liquid.
- (2) Extraction
- Ingredients Ratio: Saponified liquid: Petroleum ether = 1:1.4
- Add 0.6 times the amount of petroleum ether to the saponified liquid, stir to extract, and allow it to settle. Remove the supernatant, then extract the residue twice more with 0.4 times the amount of petroleum ether. Combine the extracts, wash with water until neutral.
- (3) Concentration, Filtration
- Concentrate the extract under reduced pressure below 40°C to 1/20 of the original volume. Cool and filter after standing at below -5°C to obtain concentrated filtrate.
- (4) Adsorption, Washing, Elution
- Ingredients Ratio: Pig heart residue: Silica gel (60-100 mesh) = 1:0.01
- Load silica gel into a purification column with a length-to-diameter ratio of 7:1. Pass the concentrated filtrate through the silica gel for adsorption. Wash the column with petroleum ether or No. 120 gasoline to remove impurities, and then elute with petroleum ether containing 5% ether until the eluate is nearly colorless.
- (5) Concentration, Crystallization, Drying
- Concentrate the eluate under reduced pressure below 40°C, remove the petroleum ether to obtain a brown oily substance. Dissolve this substance in hot anhydrous ethanol, cool to crystallize for 12 hours, filter, and vacuum dry to obtain Coenzyme Q10, with a yield of 60.9 mg per kg of fresh pig heart.
- Coenzyme Q10 Production using Squalene
- A method using waste tobacco leaves to extract squalene, which is then used to semi-synthetically produce Coenzyme Q10.
- Microbial Fermentation Method
- A technique involving microbial fermentation to produce Coenzyme Q10.
Benefits and Functions of Coenzyme Q10
- Coenzyme Q10 acts as a cofactor in the electron transport chain, involved in ATP synthesis through a series of redox reactions. Since most cell functions depend on adequate ATP supply, Coenzyme Q10 is crucial for all tissues and organs. Additionally, Coenzyme Q10 is a key lipid antioxidant, preventing the production of free radicals and changes to proteins, lipids, and DNA.
Applications of Coenzyme Q10
- Used in food, pharmaceuticals, and other industries.
Packaging and Storage
【Storage Conditions】Keep sealed, protected from light, stored in a cool, dry, well-ventilated place.
【Packaging】Bulk: 25 kg/cardboard drum; Sample: 1 kg/foil bag; Custom packaging available upon request.
【Shipping】By express or logistics. Domestic express delivery within three days, logistics within five days. Prices generally include domestic shipping costs.
【Shelf Life】Two years
Extraction Sources
- Animal sources include beef, poultry, pig liver, eggs, and fatty fish (such as herring, salmon, trout, and tuna).
- Plant sources include nuts, oranges, strawberries, spinach, cauliflower, broccoli, lentils, and soybeans.
