Blog - China FS Ingredients

What’s the price for coenzyme Q10 raw material?

September 3, 2023

It’s between 2000 and 2500 yuan per kilogram.

The benefits and effects of taking Coenzyme Q10 while trying to conceive

September 3, 2023

Taking Coenzyme Q10 while trying to conceive can effectively increase the chances of pregnancy. For men, Coenzyme Q10 can improve sperm quality, while for women, it can enhance overall health and improve the quality of eggs. For older women trying to conceive, Coenzyme Q10 can also help boost the likelihood of pregnancy. Coenzyme Q10 is a fat-soluble antioxidant, 40 times more potent than Vitamin E. It not only competes with free radicals but also restores the original antioxidant properties of oxidized Vitamin C and E. It is recommended to consult a doctor before using this supplement.

What substances is coenzyme Q10 extracted from?

September 3, 2023

Coenzyme Q10 is typically extracted from two main sources: one involves extracting ubiquinol from discarded tobacco leaves and then synthesizing coenzyme Q10. The other method, which is the safest and most advanced, uses microbial fermentation, often from pig heart, liver, or kidneys, to extract coenzyme Q10 from the fermentation broth. The extraction methods include microbial fermentation, chemical synthesis, cell culture, and bio-extraction. Coenzyme Q10 acts as an energy protector for the heart, primarily providing power to prevent atherosclerosis and combat fatigue. It’s also a strong antioxidant that helps protect body cells from damage caused by free radicals, with no toxic side effects.

Components of Coenzyme Q10

September 3, 2023

The main components of coenzyme Q10 are lipid-soluble quinone compounds, including natural fatty acid coenzyme Q10, natural diphosphate coenzyme Q10, and some nicotinamide adenine dinucleotide. Coenzyme Q10 is an important nutrient for human cells, promoting growth and development while providing protective benefits to organs such as the heart, liver, pancreas, and kidneys. It plays a crucial role in energy metabolism, supplying energy to the body, enhancing metabolism, and helping eliminate free radicals to prevent disease. Natural fats are rich in coenzyme Q10, which is a key component of human cells. Natural diphosphate coenzyme Q10 is essential for synthesizing human cells and can assist in disease treatment. Nicotinamide adenine dinucleotide, found mainly in foods like peanuts, walnuts, and almonds, is a water-soluble vitamin vital for cell synthesis. Patients can increase their physical activity, consume high-quality protein foods like milk, eggs, and lean meats, along with fresh fruits and vegetables, while ensuring adequate sleep and maintaining healthy lifestyle habits.

The effectiveness of Coenzyme Q10 for myocarditis and heart failure: Why don’t doctors recommend it?

September 3, 2023

What is Coenzyme Q10, and why are we deficient in it? Coenzyme Q10 is an antioxidant that comes from two sources: food, such as animal organs, beef, sardines, and peanuts, and our body's own synthesis process. This synthesis requires an amino acid called tyrosine, eight types of vitamins, and trace minerals. If any one of these is missing, Coenzyme Q10 cannot be produced. Therefore, our body’s natural sources of it are limited, and the materials needed for its synthesis are indispensable. Additionally, some people may experience impaired Coenzyme Q10 synthesis due to bodily dysfunction. Why do we need Coenzyme Q10? Think of the body like a car, with the mitochondria (the powerhouse of the cells) acting as the gasoline. Mitochondria require at least three types of enzymes, all of which need Coenzyme Q10 to function. Without Q10, the mitochondria can't work efficiently. In short, Coenzyme Q10 plays a critical role in helping the body produce energy, acting as a vital booster for the heart! Studies show a positive correlation between certain diseases and Coenzyme Q10 deficiency. Research has found that...

Coenzyme Q10: Everything You Need to Know!

September 3, 2023

Long read alert, manual table of contents In 1957, American biochemist Dr. Frederick Crane extracted a quinone substance from bovine heart mitochondria, marking the first discovery of Coenzyme Q10 in humans. Dr. Karl Folkers received the highest honor from the American Chemical Society—the Priestly Medal—in 1986 for being the first to determine the structure of Coenzyme Q10. Dr. Crane took Coenzyme Q10 consistently for 40 years, passing away at the age of 91. In 1961, Dr. Peter D. Mitchell from the University of Edinburgh discovered how Coenzyme Q10 generates energy at the cellular level, a groundbreaking finding that earned him the Nobel Prize in Chemistry (Physiology) in 1978. Due to its significance, the FDA has approved Coenzyme Q10 for applications related to mitochondrial diseases. In China, Coenzyme Q10 is widely used as an adjunct therapy for heart protection, hypertension, and other conditions. Many people turn to Coenzyme Q10 supplements when facing various health issues. After reading this article, you should be able to make an informed decision about the right form of Coenzyme Q10 for yourself: Coenzyme Q10 is widely...

What are the effects of Coenzyme Q10? Does Coenzyme Q10 have any side effects? What are the contraindications for using Coenzyme Q10?

September 3, 2023

Many people may have heard of Coenzyme Q10 but are unsure about which brand to choose, its benefits, potential side effects, and any usage precautions. To help you better understand Coenzyme Q10, this article will address these questions in detail, so you’ll know how to select the right CoQ10 for you. Coenzyme Q10, also known as ubiquinone, is a compound that plays a crucial role in energy production and helps combat free radicals, boost metabolism, and slow down aging—essentially making it a remarkable nutrient. Does that sound exaggerated? It might seem like an oversell, but let's take a closer look at this intriguing substance. Considering the Reduced Form of Coenzyme Q10 To provide a clear structure, here’s an outline of the article: Table of Contents 1. What is Coenzyme Q10? Let’s start with a bit of history. Coenzyme Q10 is a quinone compound, chemically similar to vitamin K. It was first isolated from beef heart mitochondria in 1957 by Frederick Crane in Wisconsin, and its structure was identified and synthesized in 1958. Coenzyme Q is a naturally occurring enzyme found...

How should CoQ10 be taken, and what is the recommended dosage?

September 3, 2023

The standard dosage of CoQ10 ranges from 90 to 200 milligrams per day, but needs may vary based on the individual and condition being treated; some studies have even used higher doses. Since CoQ10 is a fat-soluble compound, its absorption is slow and limited when taken on an empty stomach. Therefore, it's recommended to take it with meals to enhance absorption. Research has shown that taking it with fatty foods can increase intestinal absorption by up to three times.

Six Contraindications for Using CoQ10

September 3, 2023

Taking CoQ10 before bed may lead to insomnia, so it's best to take it in the morning or afternoon. During pregnancy, starting CoQ10 around the 20th week is generally considered safe; however, the safety of using it while breastfeeding is still unknown, so it's advised to avoid it. Do not use CoQ10 alongside chemotherapy drugs known as alkylating agents, as it may reduce their effectiveness. This includes medications like busulfan, carboplatin, cisplatin, cyclophosphamide, dacarbazine, and thiotepa. CoQ10 may lower blood pressure, so those with low blood pressure or those taking antihypertensive medications should use it cautiously. Relevant medications include captopril, enalapril, losartan, valsartan, diltiazem, amlodipine, hydrochlorothiazide, and furosemide. Stop using CoQ10 at least two weeks before any scheduled surgery, as it may affect blood pressure control during and after the procedure. Avoid combining CoQ10 with the anticoagulant warfarin, as CoQ10 can support blood clotting and may reduce the effectiveness of the medication. If you must take both, regular blood tests are essential to monitor clotting times, especially in the first two weeks.

Does CoQ10 Have Side Effects?

September 3, 2023

Most adults can safely take CoQ10 (Coenzyme Q10) at doses up to 3,000 milligrams daily for up to 8 months, 1,200 milligrams for 16 months, or 600 milligrams for 30 months without any significant side effects reported. However, some mild side effects have been reported, including: stomach discomfort, allergic rashes, loss of appetite, nausea, heartburn, vomiting, insomnia, fatigue, dizziness, light sensitivity, irritability, and diarrhea (especially at daily doses reaching 200 mg).

How is CoQ10 Digested and Absorbed?

September 3, 2023

The digestion and absorption of CoQ10 in the body involves several processes: Metabolism:Over 60% of orally ingested CoQ10 is excreted through urine. Absorption:CoQ10 is absorbed in the small intestine, entering the lymphatic system before reaching the bloodstream. Its hydrophobic nature and large molecular size limit its absorption, resulting in poor uptake that varies with food intake and fat content. Absorption rates are lower when taken on an empty stomach, while a high-fat diet enhances absorption. Distribution:In preclinical studies involving intravenous administration, tissues with high energy demands or metabolic activity, such as the heart, kidneys, liver, and muscles, tend to show higher levels of CoQ10.

What are the food sources of Coenzyme Q10?

September 3, 2023

This is something food lovers are most concerned about—can you get enough Coenzyme Q10 just by eating, without spending money on supplements? Animal sources of Coenzyme Q10 are relatively abundant, including beef, poultry, pork liver, eggs, and fatty fish (such as herring, salmon, and tuna). Aside from eggs, everything else seems too expensive to eat! Plant sources include: nuts, oranges, strawberries, spinach, cauliflower, broccoli, lentils, and soybeans. We used to be able to buy these, but now the price of vegetables in supermarkets is over 10 yuan per half kilo. Are you still suggesting I eat vegetables? Research shows that whether you get it from food or supplements, the absorption rate is actually not much different.

What are the characteristics of Coenzyme Q10?

September 3, 2023

Coenzyme Q10 is found in high concentrations in the heart, kidneys, liver, and muscles. In the human body, 95% of Coenzyme Q10 exists as ubiquinol (the reduced form), except in the brain and lungs, where oxidative stress is likely higher, causing ubiquinol to oxidize into ubiquinone (the oxidized form). Coenzyme Q10 plays a crucial role in the mitochondrial electron transport chain, primarily participating in the synthesis of adenosine triphosphate (ATP). ATP provides energy for muscle contraction and other essential cellular functions, so Coenzyme Q10 affects all cells, especially those with high energy demands, like the heart, lungs, liver, kidneys, spleen, pancreas, and adrenal glands. It is vital for overall health. In fact, you only need to remember one thing: "It's extremely important for health." It’s worth noting that as we age, the levels of Coenzyme Q10 in the body gradually decrease. Using age 20 as a baseline, by the time a person reaches 80, natural reductions in Coenzyme Q10 in various parts of the body are as follows: Therefore, it’s generally accepted that the heart is the organ most in...

What is Coenzyme Q10?

September 3, 2023

Coenzyme Q10 (CoQ10) is a natural antioxidant similar in structure to vitamin E and vitamin K and is a natural component found in cells. The primary functions of CoQ10 are to provide energy, act as an antioxidant, and eliminate free radicals. In short, CoQ10 can boost immunity and slow aging. A deficiency in CoQ10 can lead to issues like heart palpitations, chest tightness, fatigue, and dull skin with dark spots. Clinical data shows that CoQ10 is very safe as a dietary supplement and is widely used in cardiovascular, neurological, and oncology fields, so it can be used safely under a doctor’s guidance. Types of Coenzyme Q10CoQ10 exists in two forms: reduced (ubiquinol) and oxidized (ubiquinone), and these forms can convert into each other. However, only the reduced form (ubiquinol) is active in the body, while ubiquinone represents a small percentage. As we age, the body's natural production of CoQ10 decreases, and after age 30, the ability to metabolize CoQ10 and convert it into ubiquinol also declines. Differences Between Reduced (Ubiquinol) and Oxidized (Ubiquinone) FormsCoQ10 cannot be directly used by the...