What are the effects of Coenzyme Q10? Does Coenzyme Q10 have any side effects? What are the contraindications for using Coenzyme Q10?

Date: September 3, 2023 Categories: Industry NewsKnowledgeQ&A Views: 55

Many people may have heard of Coenzyme Q10 but are unsure about which brand to choose, its benefits, potential side effects, and any usage precautions. To help you better understand Coenzyme Q10, this article will address these questions in detail, so you’ll know how to select the right CoQ10 for you.

Coenzyme Q10, also known as ubiquinone, is a compound that plays a crucial role in energy production and helps combat free radicals, boost metabolism, and slow down aging—essentially making it a remarkable nutrient.

Does that sound exaggerated? It might seem like an oversell, but let's take a closer look at this intriguing substance.

Considering the Reduced Form of Coenzyme Q10

To provide a clear structure, here’s an outline of the article:

Table of Contents

  1. What is Coenzyme Q10?
  2. What are the characteristics of Coenzyme Q10?
  3. What are the food sources of Coenzyme Q10?
  4. How is Coenzyme Q10 digested and absorbed?
  5. What are the proven benefits of Coenzyme Q10?
  6. Does Coenzyme Q10 have side effects?
  7. Six usage precautions for Coenzyme Q10
  8. How should Coenzyme Q10 be taken? What is the recommended dosage?
  9. What forms does Coenzyme Q10 come in?
  10. High-quality Coenzyme Q10 supplements available in the U.S.
  11. Best value Coenzyme Q10 supplements in the U.S.
  12. Popular Coenzyme Q10 brands and products in China
  13. Additional notes on Heart Specialist Coenzyme Q10

1. What is Coenzyme Q10?

Let’s start with a bit of history. Coenzyme Q10 is a quinone compound, chemically similar to vitamin K. It was first isolated from beef heart mitochondria in 1957 by Frederick Crane in Wisconsin, and its structure was identified and synthesized in 1958.

Coenzyme Q is a naturally occurring enzyme found in the tissues and cells of all species, primarily located in the inner mitochondrial membrane. It is composed of a benzoquinone ring and a hydrophobic isoprenoid chain. The length of the side chain varies by species (for example, yeast primarily contains CoQ6), but in humans, Coenzyme Q mainly consists of 10 isoprenoid units, which is why it’s called Coenzyme Q10.

Most CoQ10 is synthesized in the mitochondria, with a small portion obtained through diet.

If this all sounds too technical, don’t worry—it’s more important to focus on what Coenzyme Q10 can do rather than its molecular structure.

2. What are the characteristics of Coenzyme Q10?

Coenzyme Q10 is found in high concentrations in the heart, kidneys, liver, and muscles. About 95% of Coenzyme Q10 in the body exists in its reduced form, ubiquinol, except in the brain and lungs, where oxidative stress may convert it to its oxidized form, ubiquinone.

Coenzyme Q10 is a vital mediator in the mitochondrial electron transport chain and is primarily involved in the synthesis of ATP (adenosine triphosphate), which provides energy for muscle contractions and other essential cell functions. This makes it crucial for all cells, particularly those with high energy demands, such as the heart, lungs, liver, kidneys, spleen, pancreas, and adrenal glands.

The key takeaway is: Coenzyme Q10 is extremely important for health.

It’s important to note that as we age, the levels of Coenzyme Q10 in the body gradually decline.

Using age 20 as a baseline, by age 80, the natural decline of Coenzyme Q10 in various organs is as follows:

  • Liver: 83.0%
  • Kidneys: 65.3%
  • Lungs: 51.7%
  • Heart: 42.9%

Thus, the heart is generally considered the organ that most needs supplementation of Coenzyme Q10, and many age-related heart issues can stem from low levels of this enzyme.

When reduced, Coenzyme Q10 serves as one of the body’s important lipid antioxidants, helping to lower free radical production and prevent oxidation of proteins, lipids, and DNA.

Additionally, Coenzyme Q10 can inhibit inflammatory cytokines such as TNF-α and NF-κB and affect the expression of genes related to metabolism and transport.

3. What are the food sources of Coenzyme Q10?

This is likely the most pressing question for food lovers: Can you get enough Coenzyme Q10 just through diet without spending on supplements?

Animal sources of Coenzyme Q10 are quite abundant, including beef, poultry, liver, eggs, and fatty fish (like herring, salmon, and tuna).

Aside from eggs, which are relatively inexpensive, it seems like other options might be out of reach!

Plant sources include nuts, oranges, strawberries, spinach, cauliflower, broccoli, lentils, and soybeans.

These used to be more affordable, but now vegetable prices in supermarkets are skyrocketing—can you really expect me to eat more veggies?

Research indicates that whether Coenzyme Q10 is sourced from food or supplements, the absorption rates are quite similar.

4. How is Coenzyme Q10 digested and absorbed?

The digestion and absorption of Coenzyme Q10 in the body involve several processes (translated from the American DrugBank Online website):

  1. Absorption:
    Coenzyme Q10 is absorbed in the small intestine, enters the lymphatic system, and then into the bloodstream. Its hydrophobic nature and large molecular size limit its absorption, making it less efficient. This absorption rate also varies based on food intake and the amount of fat consumed. Absorption is lower on an empty stomach but improves with high-fat meals.
  1. Distribution:
    In preclinical studies of intravenous administration, in general, tissues with high energy requirements or metabolic activity tend to show higher levels of Coenzyme Q10, including the heart, kidneys, liver, and muscles.
  2. Metabolism:
    After oral administration, more than 60% of Coenzyme Q10 is excreted from the body through urine.
    V. What are the empirical effects (effects) of Coenzyme Q10?
    In the United States, there is such a classification level of safety and effectiveness of drug ingredients. This classification basically extends to the field of dietary supplements. Here is the classification of effectiveness.
    EFFECTIVE: effective (passed FDA review process, with a large number of sufficient clinical trials, etc.)
    LIKELY EFFECTIVE: very likely to be effective (with a large number of sufficient clinical trials, etc.)
    POSSIBLY EFFECTIVE: possibly effective (one or more clinical trials, etc.)
    POSSIBLY INEFFECTIVE: possibly ineffective (one or more clinical trials, etc., proved ineffective)
    LIKELY INEFFECTIVE: very likely to be ineffective (with a large number of sufficient clinical trials, etc., proved ineffective)
    INEFFECTIVE: ineffective (more sufficient clinical trials, proved ineffective)
    INSUFFICIENT EVIDENCE: no sufficient evidence to prove
    FDA (U.S. Food and Drug Administration) has not yet approved it for the treatment of any disease, and it has been widely used as an over-the-counter drug and dietary supplement.
    The highest level of EFFECTIVE (SAFE as well) requires FDA approval, but FDA is not responsible for the review of health products. The highest certification level of health products (coenzyme Q10) is at most LIKELY EFFECTIVE.
  3. It is probably effective for the following conditions
    (1) Coenzyme Q-10 deficiency
    Taking coenzyme Q-10 by mouth seems to improve the symptoms of coenzyme Q-10 deficiency, a very rare condition. Symptoms include weakness, fatigue, and seizures.
    (2) Genetic or acquired diseases that limit energy production in the body's cells (mitochondrial diseases)
    Taking coenzyme Q-10 by mouth seems to reduce the symptoms of mitochondrial diseases; however, improvement is slow, and some people must take coenzyme Q-10 for six months to get the most benefit.
  4. It may be effective for the following conditions
    (1) Age-related vision loss (age-related macular degeneration)
    Taking a specific product containing coenzyme Q-10, acetyl-L-carnitine, and omega-3 fatty acids (phototrop) by mouth seems to improve vision in people with age-related vision loss.
    (2) Congestive heart failure (CHF)
    Some studies have shown that heart failure may be associated with low levels of coenzyme Q-10.
    Although most evidence suggests that taking Coenzyme Q-10 alone does not help treat heart failure, there is some evidence that it may help when taken in combination with other heart failure medications and therapies.
    (3) Nerve damage caused by diabetes (diabetic neuropathy)
    Studies have shown that taking Coenzyme Q-10 improves nerve damage and nerve pain in people with nerve damage caused by diabetes.
    (4) HIV/AIDS
    Oral Coenzyme Q-10 appears to improve immune function in people with HIV/AIDS.
    (5) An inherited neurological disorder called Huntington's disease
    Ubiquinol is an altered form of Coenzyme Q-10 that has been granted "orphan drug status" by the U.S. Food and Drug Administration (FDA).
    This provides Ubiquinol's manufacturers with some financial incentive to study its effectiveness against Huntington's disease, a condition so rare (affecting fewer than 200,000 people) that pharmaceutical companies may not invest in developing drugs for it.
    However, daily doses of 600 mg or less of Coenzyme Q-10 taken by mouth do not appear to be effective in slowing the progression of Huntington's disease.
    (6) High blood pressure
    Most studies show that taking Coenzyme Q-10 alone or with other drugs for high blood pressure seems to help lower blood pressure.
    However, one small study suggests that taking Coenzyme Q-10 by mouth may not lower blood pressure in people with metabolic syndrome.
    (7) Vascular complications from heart bypass surgery
    Reduced blood supply during heart or blood vessel surgery deprives tissues of oxygen. When blood supply returns to that tissue, that tissue may be damaged. There is some evidence that taking Coenzyme Q-10 by mouth one week before heart bypass or blood vessel surgery may help reduce tissue damage. However, not all studies agree with this finding.
    (8) Specific types of high blood pressure
    Taking Coenzyme Q-10 daily seems to lower systolic blood pressure (top number) in some people who have high systolic blood pressure but normal diastolic blood pressure (bottom number).
    (9) Migraines
    Taking Coenzyme Q-10 by mouth seems to help prevent migraines.
    Research shows that it can reduce the frequency of headaches by about 30% and the number of days with headache-related nausea by about 45% in adults. Taking coenzyme Q-10 also seems to reduce the frequency of migraines in children with low coenzyme Q-10 levels.
    It may take up to 3 months to see significant benefits.
    However, coenzyme Q-10 does not seem to be effective in treating migraines once they have occurred.
    (10) A genetic muscle disorder called muscular dystrophy
    Taking coenzyme Q-10 by mouth seems to improve physical function in some people with muscular dystrophy

(11) Heart attack

When taken within 72 hours of a heart attack and for one year, Coenzyme Q-10 appears to reduce the risk of heart-related events, including another heart attack, when taken starting within 72 hours of a heart attack.

(12) Parkinson's disease

Some studies suggest that taking Coenzyme Q-10 supplements may slow the decline of people with early-stage Parkinson's disease. However, taking Coenzyme Q-10 does not seem to improve symptoms in people with mid-stage Parkinson's disease.

(13) Peyronie's disease (painful erections in men)

Studies suggest that taking Coenzyme Q-10 may improve erectile function in men with painful erections.

  1. Probably not effective for the following conditions

(1) Alzheimer's disease

Taking Coenzyme Q-10 does not seem to improve mental function in people with Alzheimer's disease.

(2) A neurodegenerative disease called ALS or Lou Gehrid's disease

Studies suggest that taking Coenzyme Q-10 does not slow the progression of ALS.

(3) Cocaine dependence

Taking a combination of Coenzyme Q-10 and L-carnitine does not reduce cocaine use.

(4) High cholesterol

Some studies have shown that taking Coenzyme Q-10 does not reduce total cholesterol, triglycerides, or low-density lipoprotein (LDL or "bad") cholesterol, or increase high-density lipoprotein (HDL or "good") cholesterol.

Other studies have shown that taking Coenzyme Q-10 by mouth alone or with carnitine does not improve cholesterol levels.

However, one study in people who could not take statins showed that taking a combination of Coenzyme Q-10, berberine, polyicosanol, red yeast rice, folic acid, and astaxanthin lowered cholesterol levels.

(5) Symptoms affecting polio survivors (post-polio syndrome)

Studies have shown that taking Coenzyme Q-10 does not improve muscle strength or muscle function in people with post-polio syndrome.

  1. May not be effective for the following conditions

Athletic performance. Oral coenzyme Q-10 does not improve athletic performance in athletes or non-athletes.

  1. There is insufficient evidence to assess its effectiveness in the following conditions

(1) Chest pain (angina).

Some early studies suggest that oral coenzyme Q-10 may improve exercise tolerance in people with angina.

(2) Asthma.

Some early studies suggest that taking coenzyme Q-10, vitamin E (alpha-tocopherol), and vitamin C in addition to conventional asthma treatment may reduce the dose of medication needed in people with mild to moderate asthma.

(3) Breast cancer.

Some studies of Chinese women suggest that low blood levels of coenzyme Q-10 are associated with an increased risk of breast cancer.

There is preliminary evidence that taking oral coenzyme Q-10 along with surgery and conventional treatment and other antioxidants and omega-3 and omega-6 fatty acids may help with advanced breast cancer.

(4) Cancer.

Studies suggest that low coenzyme Q-10 levels are associated with an increased risk of skin cancer. In addition, early studies suggest that taking Coenzyme Q-10 along with other antioxidants may extend the survival time of people with advanced cancer by 40%.

(5) Cardiotoxicity caused by chemotherapy drugs.

Some studies suggest that taking Coenzyme Q-10 by mouth may protect the hearts of children and adults receiving the chemotherapy drug anthracyclines. However, other studies suggest that taking Coenzyme Q-10 intravenously (by IV) does not provide this benefit.

(6) A lung disease called chronic obstructive pulmonary disease (COPD).

Early studies suggest that taking Coenzyme Q-10 may improve lung function and exercise tolerance in people with COPD.

(7) Cyclic vomiting syndrome.

Some early studies suggest that taking Coenzyme Q-10 may be as effective as prescription drugs used to treat cyclic vomiting syndrome.

(8) Diabetes.

Research on the effectiveness of Coenzyme Q-10 for diabetes is conflicting. Some studies suggest that taking Coenzyme Q-10 may lower blood sugar levels. However, other studies have not found any benefit.

(9) Weakened and enlarged heart (dilated cardiomyopathy).

Early evidence suggests that taking coenzyme Q-10 may improve heart function in children with dilated cardiomyopathy.

(10) Dry mouth.

Early research suggests that taking coenzyme Q-10 (ubiquinol) may improve dry mouth.

(11) Eye surgery.

Research suggests that using eye drops containing coenzyme Q-10 and vitamin E may increase the rate of nerve regeneration after cataract eye surgery.

(12) Fibromyalgia.

Some early research suggests that taking coenzyme Q-10 and ginkgo may increase feelings of well-being and overall well-being and reduce pain in people with fibromyalgia.

(13) Incoordination of movements due to brain damage (cerebellar ataxia).

Early research suggests that coenzyme Q-10 may improve muscle coordination and movement in people with cerebellar ataxia.

(14) A rare genetic disease that causes nerve damage (Friedreich's ataxia).

Early research suggests that taking vitamin E with coenzyme Q-10 may improve coordination, posture, and movement in people with Friedreich's ataxia.

(15) Hearing loss.

Research suggests that taking a specific coenzyme Q-10 product (Q-TER) by mouth may improve hearing in people with age-related hearing loss. However, combining coenzyme Q-10 with traditional steroid treatment does not improve hearing more than steroid treatment alone.

(16) Hepatitis C.

Research suggests that taking coenzyme Q-10 does not improve liver function in people with hepatitis C who do not respond to conventional treatment.

(17) A heart disease called hypertrophic cardiomyopathy.

Taking coenzyme Q-10 by mouth appears to reduce the thickness of the heart wall and reduce symptoms of shortness of breath and fatigue in people with hypertrophic cardiomyopathy.

(18) A rare genetic disease called Prader-Willi syndrome.

Early studies suggest that giving coenzyme Q-10 may improve development in children with Prader-Labhart-Willi syndrome. However, it is not clear whether these improvements are due to coenzyme Q-10 or are age-related phenomena.

(19) Male infertility.

There is some early evidence that coenzyme Q-10 treatment may improve sperm motility and density in men with certain types of infertility. However, other studies have shown that it has no beneficial effects on sperm motility.

(20) Genetic diabetes and deafness.

There is some early evidence that taking coenzyme Q-10 by mouth may prevent the progression of a rare type of diabetes that is inherited from the mother.

(21) Gum disease.

Applying coenzyme Q-10 to the gums is not effective for treating gum disease. However, there is some early evidence that taking coenzyme Q-10 by mouth may help treat gum disease.

(22) High blood pressure during pregnancy (preeclampsia).

Preeclampsia is a condition that some women develop during pregnancy. Some studies suggest that women at risk may have a lower chance of developing the disease if they take coenzyme Q-10 from the 20th week of pregnancy until the baby is born.

(23) Prostate cancer.

Studies suggest that taking vitamin E, selenium, vitamin C, and coenzyme Q-10 together does not improve prostate cancer.

(24) Kidney failure.

Some early studies suggest that taking coenzyme Q-10 may improve kidney function in people with end-stage renal disease. However, other studies suggest that taking coenzyme Q-10 does not improve kidney function.

(25) A muscle disease called "statin-induced myopathy."

Statins are a class of drugs used to lower cholesterol that sometimes cause muscle pain. There is some evidence that taking coenzyme Q-10 may reduce this pain. However, not all the evidence is positive.

(26) Hair loss associated with warfarin use.

There is some early evidence that taking coenzyme Q-10 may help prevent hair loss caused by the blood-thinning drug warfarin.

(27) Wrinkled skin.

Early evidence suggests that applying a coenzyme Q-10 cream to the skin can improve wrinkled skin.

(28) Fatigue.

(29) Lyme disease.

Other conditions.

More evidence is needed to evaluate these uses of coenzyme Q-10.

The Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence on the following scale: Effective, Likely Effective, Possibly Effective, Likely Not Effective, Likely Not Effective, and Rating Insufficient Evidence (with detailed descriptions of each rating).

NYO3 Norvaga Reduced Coenzyme Q10 Soft Capsules 30 Capsules 99% High Purity Marine Phosphorus

JD.com

¥336.00

Go to buy

VI. Does Coenzyme Q10 have side effects?

Most adults take coenzyme Q10 (Coenzyme Q10) orally safely at doses up to 3000 mg per day for 8 months; 1200 mg per day for 16 months; and 600 mg per day for 30 months, with no significant side effects reported.

The minor side effects that have been reported include: stomach discomfort, allergic rash, loss of appetite, nausea, heartburn, vomiting, insomnia, fatigue, dizziness, photosensitivity, irritability and diarrhea (especially at a daily dose of 200 mg).

VII. 6 contraindications for the use of Coenzyme Q10

  1. During pregnancy, it is safe to take Coenzyme Q10 (Coenzyme Q10) starting from about 20 weeks of pregnancy; however, the safety of use during breastfeeding is still unknown, so it is recommended not to use it.
  2. Do not use with chemotherapy drugs: alkylating agents. Coenzyme Q10 may reduce the effectiveness of these drugs. Related drug names include: busulfan, carboplatin, cisplatin, cyclophosphamide, dacarbazine, thiotepa
  3. Coenzyme Q10 may have a blood pressure lowering effect, so patients with low blood pressure or those taking antihypertensive drugs should use it with caution. Related drugs include: captopril, enalapril, losartan, valsartan, diltiazem, amlodipine, hydrochlorothiazide, furosemide
  4. Stop using it two weeks before the scheduled surgery because Coenzyme Q10 may affect blood pressure control during and after surgery.
  5. Do not use it with the anticoagulant Warfarin, because Coenzyme Q10 helps blood coagulation. If used together, it will reduce the effectiveness of the drug. If you need to use warfarin and Coenzyme Q10 at the same time, be sure to have regular blood tests to evaluate the coagulation time, especially in the first two weeks.
  6. Taking it before bed may cause insomnia, so it is best to take it in the morning or afternoon.

VIII. How to take Coenzyme Q10? What is the dosage?

The standard dose of CoQ10 ranges from 90 mg to 200 mg per day. The demand may vary depending on the person being treated and the situation. Some studies have even used higher doses.

Because CoQ10 is a fat-soluble compound, its absorption is slow and limited when used on an empty stomach. Therefore, it is recommended to take it with meals to accelerate absorption.

Experiments have found that intestinal absorption can be accelerated by 3 times if taken with oily foods.

IX. What dosage forms of Coenzyme Q10 are there?

In the human body, CoQ10 exists in two different forms, namely the reduced form ubiquinol and the oxidized form ubiquinone, with ubiquinol accounting for 90% of CoQ10 in the blood.

Both forms are helpful in increasing the circulating levels of CoQ10 in the body.

In a study comparing the two forms, the plasma concentration of reduced ubiquinol increased 4.77 times after 4 weeks of use, compared to 2.77 times of oxidized ubiquinone, which shows that the bioavailability of ubiquinol is significantly higher (about 1.72 times higher, but relatively speaking, the price of related supplements is also more expensive).

The content is too long and I can't read it anymore. What should I do? I just want to know what brand of CoQ10 is good to buy?

  1. CoQ10 health products with better quality in the United States

Labdoor selected 25 brands of CoQ10 health products for evaluation, and the following is the ranking of the top ten.

Evaluation criteria

Label Accuracy, testing whether the actual content of the product is consistent with the label.

Product Purity, testing whether the product contains six heavy metals (cadmium, lead, cadmium, bismuth, antimony and silver). Fortunately, all the products participating in the evaluation passed the test (<2PPM).

Nutritional Value, testing the nutrients and calories contained in the product. Coenzyme Q10 is not one of the nutrients we consume daily and contains almost no calories. Some products use sugar as an auxiliary material, which will provide a small amount of calories.

Ingredient Safety, testing whether the product content exceeds the maximum tolerance value of the human body. At present, there is no maximum tolerance value standard for coenzyme Q10, and there are no obvious side effects even if 1200mg is consumed daily.

Projected Efficacy, testing whether the product content reaches the effective dose. For patients with heart failure and hypertension, the recommended supplement amount is at least 100-200mg per day.

Ranking Brand Coenzyme Q10 Content 1Bulk Supplements 196.7 mg 2Garden Of Life 196.1 mg 3Solgar Vegetarian 212.7 mg 4Kirkland Signature 302.4 mg 5Nature Made 197.2 mg 6Nature’s Bounty 205.9 mg 7NutriONN 192.1 mg 8Viva Labs 104.5 mg 9Source Naturals 108.3 mg 10Nutrigold 98.1 mg

The scores of the ten Coenzyme Q10 products in the above ranking are actually very close and comparable.

Most products have a dosage of 200 mg/serving, and the actual content differs by only a few milligrams.

For health purposes, it is enough.

Costco’s own brand Kirkland Signature has a higher dosage of 300 mg/serving.

It should be noted that the No. 1 Bulk Supplements Pure Coenzyme Q10 is in powder packaging, and you need to use a measuring spoon to take out 200mg and dissolve it in a drink or food.

Other products are in capsule packaging. The most common coenzyme in American supermarkets is Nature Made

Q10.

XI. The most cost-effective coenzyme Q10 health supplement in the United States

Ranking Brand Coenzyme Q10 Content 1Viva Labs 104.5 mg 2Doctor’s Best 103.1 mg 3Puritan’s Pride 100.2 mg 4Nature’s Bounty 205.9 mg 5Kirkland Signature 302.4 mg 6Nutrigold 98.1 mg 7Bulk Supplements 196.7 mg 8NOW Foods 89.5 mg 9Source Naturals 108.3 mg 10GNC 102 mg

After considering the price factor, several products with a lower dose of 100 mg/serving ranked first. For ordinary people without heart disease, this dose has reached the daily health dose.

Since coenzyme Q10 is fat-soluble, it is recommended to take it with meals.

  1. Brands and products of coenzyme Q10 with good sales in China

Ranking Brand Coenzyme Q10 Content 1Puritan's Pride 200mg/tablet 2Swisse 150mg/tablet 3Schiff MegaRed 200mg/tablet 4By-Health 29.8mg/tablet 5Blackmores 150mg/tablet 6GNC 200mg/tablet 7-Day Nature Made 200mg/tablet 8NovaSOL 200mg/tablet 9Doctor's Best 200mg/tablet 10Doppelherz 50mg/tablet

Important correction: Some netizens pointed out that the coenzyme Q10 content of By-Health in this article was wrongly marked. I consulted By-Health's customer service and it was indeed my mistake. The correct data should be "Each tablet contains: Coenzyme Q10 29.8mg, Vitamin E 16.08mg", 400mg/capsule is the weight of each capsule, not the content of coenzyme Q10.

Jingdong purchase link:

There are actually 6 specifications of Puli Pulai's coenzyme sold on Jingdong:

  1. 100 mg specification for staying up late to protect the heart
  2. 100 mg two bottles of specifications
  3. 120 mg specification for enhanced heart protection
  4. 200 mg specification for heart protection and pregnancy preparation
  5. 400 mg specification for strong heart protection
  6. 100 mg specification of panthenol

You can choose according to your actual situation.

Thirteen, additional explanation on Xindaren Coenzyme Q10

Some friends said in the comments how can we miss Xindaren's coenzyme, mainly because many people have introduced this brand on Zhihu before, I think there is no need to add to it, but since some friends have made this request, then I will add it.

The brand Xindaren is from the United States. The reduced coenzyme sold in China (specifically JD.com here) is 30 capsules, which is the Ubiquinol type coenzyme we introduced earlier.

Its feature is that it uses the industry's top MicroActive technology, which can achieve rapid absorption within 6 hours and continuous absorption for 24 hours, which is 40% more absorption than the reduced coenzyme Q10 product, promotes cell health, helps maintain cardiovascular health, and can double the level of coenzyme Q10 in the body within 3 weeks.

In addition, WaterDipersible technology is used, which is more conducive to intestinal absorption.

Some friends may be curious about what MicroActive technology is. Here is a brief introduction:

Coenzyme Q10 is a fat-soluble ingredient. Generally speaking, absorption has always been a problem. There are roughly several technologies on the market for promoting Q10 absorption, including emulsification (pre-emulsification, characterized by tocopherol), additives (BioPerine, D-lemon oil), liposome technology (Mega-Liposomal), NovaSOL technology, MicroActive technology, etc.

The better coenzyme Q10 products currently use MicoActive® water-soluble coenzyme Q10 technology, which increases the peak absorption by 800% compared to traditional coenzyme Q10 products.

Original patent text of MicroActive®

The above curve is probably the human absorption curve of MicroAcitve® coenzyme Q10

The following is the human absorption curve of traditional Crystalline coenzyme Q10

MicroAcitve® is about 4 times more efficient than traditional Crystalline coenzyme Q10.

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