Coenzyme Q10 (CoQ10) is a natural antioxidant similar in structure to vitamin E and vitamin K and is a natural component found in cells. The primary functions of CoQ10 are to provide energy, act as an antioxidant, and eliminate free radicals. In short, CoQ10 can boost immunity and slow aging. A deficiency in CoQ10 can lead to issues like heart palpitations, chest tightness, fatigue, and dull skin with dark spots. Clinical data shows that CoQ10 is very safe as a dietary supplement and is widely used in cardiovascular, neurological, and oncology fields, so it can be used safely under a doctor’s guidance.
Types of Coenzyme Q10
CoQ10 exists in two forms: reduced (ubiquinol) and oxidized (ubiquinone), and these forms can convert into each other. However, only the reduced form (ubiquinol) is active in the body, while ubiquinone represents a small percentage. As we age, the body's natural production of CoQ10 decreases, and after age 30, the ability to metabolize CoQ10 and convert it into ubiquinol also declines.
Differences Between Reduced (Ubiquinol) and Oxidized (Ubiquinone) Forms
CoQ10 cannot be directly used by the body; it needs to be converted into ubiquinol first. Studies show that ubiquinol has a much better absorption rate than ubiquinone, and 95% of the CoQ10 in the bloodstream is in the form of ubiquinol.
Ubiquinol (Reduced Form):
- The biggest advantage of ubiquinol is that its absorption rate is several times higher than that of ubiquinone, making it easier for the body to absorb.
- Ubiquinol has antioxidant properties, which oxidized CoQ10 (ubiquinone) lacks.
- Although the body can synthesize CoQ10, ubiquinol is the more bioavailable form, making it a better choice for high-risk groups.
Ubiquinone (Oxidized Form):
Ubiquinone must first be converted into ubiquinol by the body before it can be used, but the efficiency of this conversion decreases with age or disease.
Summary
Most CoQ10 supplements on the market are in the "oxidized" form, but the majority of the CoQ10 in our bodies exists in the "reduced" form. The oxidized form we consume needs to be converted into the reduced form in the body, but this conversion ability declines with age. If you feel like the CoQ10 you’ve been taking isn’t effective, it might be because you’ve been taking the "oxidized" form. Additionally, foods rich in CoQ10, like fish, meat, soybeans, and sesame oil, don’t provide enough to meet the body’s needs. For example, you'd need to eat dozens of fish to get the required amount. Therefore, reduced CoQ10 supplements offer a more convenient and direct way to get the benefits.
