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Product Overview
Resveratrol is a non-flavonoid phenolic compound, a plant antioxidant belonging to the stilbene class. It is produced by plants to defend against bacterial or fungal infections. Natural sources of resveratrol include grape skins, blueberries, raspberries, mulberries, and peanuts. Currently, industrial production mainly extracts resveratrol from Japanese knotweed. According to the "Directory of Cosmetic Ingredients (2015 Edition)" issued by the former State Food and Drug Administration, resveratrol is listed with the serial number 01152. It is also recognized by the "Anti-Aging Bible" in the U.S. as one of the "100 Most Effective Anti-Aging Substances."
Resveratrol Production Process
- Natural Plant Extraction
Using grapes, knotweed, and peanuts as raw materials, resveratrol is extracted and purified. Common extraction methods include organic solvent extraction, alkaline extraction, and enzyme extraction, with new methods such as microwave-assisted extraction, CO2 supercritical extraction, and ultrasonic-assisted extraction also being applied. The purification process primarily separates the cis- and trans-isomers and resveratrol derivatives to obtain trans-resveratrol. Common purification methods include chromatography, silica gel column chromatography, thin-layer chromatography, and high-performance liquid chromatography.
- Synthetic Methods
Given the low natural content of resveratrol in plants and high extraction costs, chemical, biological, and genetic engineering methods are increasingly used to produce resveratrol. Established chemical synthesis methods include Perkin reaction, Hech reaction, and Witting-Horner reaction, with yields of 55.2%, 70%, and 35.7%, respectively. Genetic engineering techniques can be used to control or enhance resveratrol biosynthesis in plants, and mutation breeding can improve yield by 1.5 to 3.0 times.
Resveratrol Benefits and Functions
- Anti-aging
- Anti-cancer mechanisms
- Cardiovascular health
- Other effects: Resveratrol also has antimicrobial, antioxidant, immune-modulating, and anti-asthmatic properties. Its various biological activities make resveratrol highly sought after.
Resveratrol Applications
Used in health foods, pharmaceuticals, cosmetics, and other areas.
Packaging and Storage
【Storage Conditions】 Keep sealed, protect from light, avoid high temperatures. Store in a dry, cool, and well-ventilated place.
【Packaging】 Bulk: 25 kg per cardboard drum; samples: 1 kg per aluminum foil bag. Custom packaging available upon request.
【Transportation】 By express or logistics. Domestic express delivery within three days, logistics within five days. Prices generally include domestic shipping costs.
【Shelf Life】 Two years
Extraction Source—Japanese Knotweed
Research shows that resveratrol is found in various plants including mulberry, peanuts, knotweed, and others. For better utilization of resveratrol plant resources, literature has been reviewed to summarize the distribution of resveratrol in different plant families, genera, and organs.
According to Table 1, resveratrol is sourced from 34 families, 69 genera, and 100 plant species. The highest resveratrol content is found in the seeds of the peony (Paeonia) of the Ranunculaceae family at 870.0 μg/g, followed by Japanese knotweed roots at 420.9 μg/g.
Japanese knotweed (Reynoutria japonica Houtt.) is a perennial herb in the Polygonaceae family. It has thick rhizomes, upright stems that can reach 2 meters in height, and is hollow. The leaves are wide-ovate or ovate-elliptic, somewhat leathery, hairless on both sides, tapering to a point at the tip, with a wide wedge-shaped or truncate base. The stipules are membranous, with a racemose inflorescence. Flowers are unisexual, dioecious, and axillary; bracts are funnel-shaped, sepals are pale green, and the achenes are glossy brown. It flowers from August to September and fruits from September to October. It is found in Shaanxi, Gansu, East China, Central China, South China, Sichuan, and other areas; also distributed in Korea and Japan. It grows in hillside shrubs, valleys, roadsides, and wet fields. The rhizome is used medicinally for its blood-activating, bruising, menstrual-regulating, and cough-relieving effects.
