Product Description

Polygonum cuspidatum emodin is a derivative of stilbene, including compounds such as emodin, aloe acid, and other stilbene derivatives. It is one of the effective components in Polygonum cuspidatum emodin and is extracted from plants like rhubarb, Fo-ti, cassia seeds, and knotweed. The extraction methods include maceration, reflux extraction, and supercritical extraction, known for their efficiency, speed, simplicity, and low temperature advantages. Polygonum cuspidatum emodin, present in various medicinal herbs like knotweed, has broad pharmacological effects and significant clinical application value.

Polygonum cuspidatum emodin typically appears as orange-yellow, needle-like crystals. It crystallizes orange in acetone, yellow in methanol, with a melting point of 256°C–257°C. It has a specific anthraquinone reaction, is nearly insoluble in water but soluble in ethanol and alkaline solutions.

The plant source of Polygonum cuspidatum emodin is the dried rhizome and root of the knotweed plant. It is a plant-derived medicine.

The physiological activity of Polygonum cuspidatum emodin means it is not only used for medical purposes but also in health products and daily chemicals, such as hair and skin care products, and natural dyes. Internationally, it is also used as a mild laxative.

Production Process of Polygonum cuspidatum emodin

  1. Conventional Extraction Method: Ethanol is commonly used as a solvent for extracting Polygonum cuspidatum emodin . The ethanol reflux extraction process is preferred.
  1. Supercritical Fluid CO2 Extraction Method: This is a high-efficiency, clean, and advanced technology that uses supercritical CO2 as a solvent to extract and separate the active components.

Pharmacological Research on Polygonum cuspidatum emodin

Anti-inflammatory: Studies show it inhibits swelling caused by carrageenan in mice, with effects increasing with dosage. It also significantly reduces the increase in capillary permeability caused by acetic acid and inhibits exudation and leukocyte migration in acute pleurisy induced by carrageenan.

Antibacterial: Polygonum cuspidatum emodin has broad-spectrum antibacterial properties, is less likely to develop resistance, and is effective against various bacteria including Staphylococcus aureus, Streptococcus, diphtheria, Bacillus cereus, anthrax, Salmonella, Shigella, influenza bacteria, and pneumococcus, with strong inhibition against anaerobic bacteria.

Antiviral: It inhibits viruses such as Hepatitis B, cytomegalovirus, EB virus, coronavirus, poliovirus, and herpes simplex virus. Studies show combinations of Polygonum cuspidatum emodin with other herbal components have high efficacy against certain viruses. Polygonum cuspidatum emodin's antiviral action primarily works by inhibiting viral adsorption and entry, preventing replication.

Antifungal: Screening shows Polygonum cuspidatum emodin has antifungal activity against species in the Rubiaceae and Rhamnaceae families.

Antiprotozoal: It exhibits extensive activity against protozoa including Trypanosoma brucei, Leishmania donovani, and Plasmodium falciparum.

Packaging and Storage of Polygonum cuspidatum emodin

Storage Conditions: Keep sealed and protected from light, avoid high temperatures, and store in a cool, dry, well-ventilated place.

Packaging: Bulk in 25 kg cardboard barrels, small samples in 1 kg aluminum foil bags, or customized packaging as per customer requirements.

Transport: Express or logistics; domestic delivery within three days by express, and within five days by logistics. Prices usually include domestic shipping costs.

Shelf Life: Two years

Plant Source—Japanese Knotweed

Japanese Knotweed (scientific name: Reynoutria japonica Houtt.) is also known as Flower-spotted Bamboo, Sour Pipe Stem, Sour Soup Stem, Sichuan Muscle Dragon, Spotted Cluster, and Spotted Stick Root. Japanese Knotweed is used for ornamental purposes, as food (young stems as vegetables, roots for cold drinks), and for medicinal purposes. It is a herbaceous plant of the buckwheat family, with small white flowers on separate plants, and an inflorescence in leaf axils. The fruit is reddish-brown with broad wings. The rhizomes are harvested in autumn and winter, sliced, and dried. It is distributed in central and southern China, growing in moist areas like valleys and stream banks. It is used to treat damp heat jaundice, urinary tract infections, vaginal discharge, rheumatic pain, carbuncles, burns, menstrual disorders, cysts, bruises, and coughs from lung heat.

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