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Product Description
Amygdalin, also known as Vitamin B17, bitter almond glycoside, or apricot glycoside, is an organic compound belonging to the aromatic cyanogenic glycosides class. It has been studied for nearly 200 years. It is the primary active component in bitter almonds and is widely found in seeds of plants in the Rosaceae family such as apricots, peaches, and plums, with particularly high concentrations in bitter almonds, reaching up to 2%-3%.
Amygdalin is a β-cyanogenic glycoside that contains a cyanide group (CN). When bitter almonds are consumed, it releases free cyanide, which can be toxic. Amygdalin is a product of the metabolism of phenylalanine in bitter almonds. Bitter almonds contain β-glucosidase and mandelonitrile hydrolase; the former catalyzes the hydrolysis of amygdalin into two molecules of glucose and one molecule of mandelonitrile, while the latter catalyzes the hydrolysis of mandelonitrile into cyanide (HCN) and benzaldehyde. Amygdalin is present in seeds such as almonds.
Bitter almonds contain 3% amygdalin. Enzymatic hydrolysis of amygdalin forms hydrocyanic acid, which is toxic but has a sedative effect on the respiratory center in small amounts. Literature records its use for cough relief and as an antibacterial agent against typhoid and other bacteria. Recent research has shown that hydrocyanic acid also has anticancer properties, making it beneficial for human health.
Solubility: Amygdalin has a solubility of 83g/L in water (25°C), dissolves in 12ml of water, 900ml of ethanol, and 11ml of boiling ethanol. It is easily soluble in boiling water, with a near-neutral pH in aqueous solution.
Amygdalin Production Process
Cleaning -> Sorting -> Grinding -> Defatting -> Ethanol Extraction -> Concentration -> Decolorization and Purification -> Crystallization -> Centrifugation -> Drying -> Grinding -> Testing -> Packaging -> Storage
Amygdalin Applications
Amygdalin is widely used in the pharmaceutical industry.
Category: Toxic substance.
Toxicity Level: High toxicity.
Acute Toxicity: Oral - Rat LD50: 522 mg/kg; Oral - Mouse LD50: 443 mg/kg.
Amygdalin Packaging and Storage
【Storage Conditions】Keep sealed and protected from light, store in a dry, cool, well-ventilated place.
【Packaging】Bulk in 25kg cardboard drums; small samples in 10g-1kg aluminum foil bags, with custom packaging available.
【Shipping】Courier or logistics; domestic courier within three days, logistics within five days. Pricing generally includes domestic shipping costs.
【Shelf Life】Two years.
Plant Source—Bitter Almond
Bitter almonds, also known as apricot kernels. Latin name: Semen Armeniacae Amarum. Derived from the Prunus armeniaca tree, the ripe fruit is harvested in summer, with the flesh and shell removed to extract and dry the seeds. Bitter almonds are a commonly used traditional Chinese medicine, known for its functions such as relieving cough, asthma, and improving bowel movements. It is used for coughs, asthma, chest congestion with phlegm, blood deficiency, and constipation. Bitter almond oil has insecticidal and antibacterial properties, effective against roundworms and earthworms, and has antimicrobial activity against typhoid and paratyphoid bacteria. The fatty oil in bitter almonds can soften the skin, moisturize, protect peripheral blood vessels and organs, and inhibit bacterial growth.
