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Product Overview
Hyaluronic acid, also known as hyaluronic acid, has the molecular formula (C14H21NO11)n and is a glycosaminoglycan composed of D-glucuronic acid and N-acetylglucosamine. Hyaluronic acid is an acidic polysaccharide first isolated from the vitreous body of cow eyes in 1934 by Professor Meyer at Columbia University. Due to its unique molecular structure and physicochemical properties, it serves various important physiological functions in the body, such as lubricating joints, regulating the permeability of blood vessel walls, balancing protein and electrolyte diffusion and movement, and promoting wound healing.
Hyaluronic Acid Production Process
The production process and technology for hyaluronic acid determine its quality. For therapeutic effects, it is crucial to use products from reliable sources. Common extraction methods include:
- Animal Tissues: Mainly chicken combs and cow vitreous body. The process involves defatting and dehydrating the raw material with acetone or ethanol, soaking and filtering with distilled water, treating with sodium chloride solution and chloroform, then adding protease and incubating to obtain a mixture, and finally purifying with ion exchange agents. This method has a very low extraction rate (about 1%), complex separation process, and high cost (about $5000 per kilogram), limiting its use in cosmetics.
- Microbial Fermentation: Using glucose as a carbon source for fermentation in a culture medium for 48 hours, then filtering out the mycelium and impurities. The high-purity product is obtained through simple operations such as alcohol precipitation. Fermentation has the advantage of allowing control over molecular weight, and the key is choosing the right strain, typically streptococcus or lactobacillus.
- Chemical Synthesis: Uses natural enzyme polymerization; first, polysaccharide polymers are synthesized into "hyaluronic acid oxazolidinone derivatives," then water-splitting enzymes are added to create a derivative-enzyme complex, and finally, the enzyme is removed at 90°C to synthesize hyaluronic acid. Chemical synthesis can significantly reduce production costs, but the structure may be less pure.
Currently, hyaluronic acid is primarily produced by fermentation, with Huaxi Biological being a leading domestic company in this production method and the first to implement this technology in China.
Benefits and Effects of Hyaluronic Acid
- Moisturizing: Small molecules in hyaluronic acid lock in moisture, penetrate the stratum corneum, and provide hydration, making the skin plump and radiant.
- Anti-Aging: Hyaluronic acid promotes collagen regeneration. As we age, skin becomes loose, but using hyaluronic acid can diminish forehead lines, smile lines, and nasolabial folds, helping the skin regain elasticity and firmness, thus providing anti-aging benefits.
- Contouring.
Hyaluronic Acid Application Scenarios
It is a biopharmaceutical with high clinical value, widely used in various eye surgeries, such as lens implantation, corneal transplantation, and anti-glaucoma surgeries. It can also treat arthritis and accelerate wound healing. In cosmetics, it provides unique skin protection, keeps the skin moisturized, smooth, delicate, and elastic, and has anti-wrinkle, beauty maintenance, and skin function restoration effects.
Packaging and Storage
【Storage Conditions】Seal tightly, protect from light, avoid high temperatures, and store in a dry, cool, well-ventilated place.
【Packaging】Bulk: 25 kg per cardboard drum; samples: 1 kg per foil bag, or packaged according to customer requirements.
【Shipping】Express or logistics. Domestic express delivery within three days; logistics within five days. Quotes generally include domestic shipping costs.
【Shelf Life】Two years
